<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="6.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Thompson, O.B.</style></author><author><style face="normal" font="default" size="100%">Andrews, M.K.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Tissue perfusion measurements: Multiple-exposure laser speckle analysis generates laser doppler-like spectra</style></title><secondary-title><style face="normal" font="default" size="100%">Journal of Biomedical Optics</style></secondary-title></titles><keywords><keyword><style  face="normal" font="default" size="100%">algorithm</style></keyword><keyword><style  face="normal" font="default" size="100%">Algorithms</style></keyword><keyword><style  face="normal" font="default" size="100%">article</style></keyword><keyword><style  face="normal" font="default" size="100%">Biomedical optics</style></keyword><keyword><style  face="normal" font="default" size="100%">Blood</style></keyword><keyword><style  face="normal" font="default" size="100%">Brownian movement</style></keyword><keyword><style  face="normal" font="default" size="100%">Classifiers</style></keyword><keyword><style  face="normal" font="default" size="100%">computer assisted diagnosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Computer simulation</style></keyword><keyword><style  face="normal" font="default" size="100%">Computer-Assisted</style></keyword><keyword><style  face="normal" font="default" size="100%">Diagnosis</style></keyword><keyword><style  face="normal" font="default" size="100%">Doppler effect</style></keyword><keyword><style  face="normal" font="default" size="100%">human</style></keyword><keyword><style  face="normal" font="default" size="100%">Humans</style></keyword><keyword><style  face="normal" font="default" size="100%">Image quality</style></keyword><keyword><style  face="normal" font="default" size="100%">Imaging</style></keyword><keyword><style  face="normal" font="default" size="100%">instrumentation</style></keyword><keyword><style  face="normal" font="default" size="100%">Laser doppler</style></keyword><keyword><style  face="normal" font="default" size="100%">laser Doppler flowmetry</style></keyword><keyword><style  face="normal" font="default" size="100%">Laser speckle</style></keyword><keyword><style  face="normal" font="default" size="100%">Laser speckle contrast analysis</style></keyword><keyword><style  face="normal" font="default" size="100%">Laser speckle perfusion imaging</style></keyword><keyword><style  face="normal" font="default" size="100%">Laser-Doppler Flowmetry</style></keyword><keyword><style  face="normal" font="default" size="100%">methodology</style></keyword><keyword><style  face="normal" font="default" size="100%">Perfusion</style></keyword><keyword><style  face="normal" font="default" size="100%">Perfusion Imaging</style></keyword><keyword><style  face="normal" font="default" size="100%">Phantoms</style></keyword><keyword><style  face="normal" font="default" size="100%">Power spectral density</style></keyword><keyword><style  face="normal" font="default" size="100%">reproducibility</style></keyword><keyword><style  face="normal" font="default" size="100%">Reproducibility of Results</style></keyword><keyword><style  face="normal" font="default" size="100%">scintigraphy</style></keyword><keyword><style  face="normal" font="default" size="100%">Sensitivity and Specificity</style></keyword><keyword><style  face="normal" font="default" size="100%">Speckle</style></keyword><keyword><style  face="normal" font="default" size="100%">Spectral density</style></keyword><keyword><style  face="normal" font="default" size="100%">Tissue</style></keyword></keywords><dates><year><style  face="normal" font="default" size="100%">2010</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">http://www.scopus.com/inward/record.url?eid=2-s2.0-77956642070&amp;partnerID=40&amp;md5=1e2a5983b8484df84683d07dbb8ecce5</style></url></web-urls></urls><number><style face="normal" font="default" size="100%">2</style></number><volume><style face="normal" font="default" size="100%">15</style></volume><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">Variations in skin perfusion are easily detected by laser speckle contrast maps, but a robust interpretation of the information has been lacking. We show that multiple-exposure laser speckle methods produce the same spectral information as laser Doppler methods when applied to targets with embedded moving scatterers. This enables laser speckle measurements to be interpreted more quantitatively. We do this by using computer simulation of speckle data, and by experimental measurements on Brownian motion and skin perfusion using a laser Doppler system and a multiple-exposure laser speckle system. The power spectral density measurements of the light fluctuations derived using both techniques are exactly equivalent. Dermal perfusion can therefore be measured by laser Doppler or laser speckle contrast methods. In particular, multiexposure laser speckle can be rapidly processed to generate a full-field map of the perfusion index proportional to the concentration and mean velocity of red blood cells. © 2010 Society of Photo-Optical Instrumentation Engineers.</style></abstract></record></records></xml>